Assuntos
Humanos , Feminino , Idoso , Biópsia , Clostridium , Gastroscopia , Neoplasias , Sarcina , Pacientes , EstômagoRESUMO
We present the cases of two women aged 75 and 71 years under study for dyspepsia and weight loss. The initial gastroscopy of both patients showed a stomach full of food content, with thickened gastric folds that were hard on contact with the forceps. Gastric biopsies showed the presence of Sarcina ventriculi on active chronic gastritis, so antibiotic treatment was started (ciprofloxacin and metronidazole), without significant clinical improvement. In both patients, gastroscopy was repeated without showing macroscopic changes compared to the initial gastroscopy, which led to the suspicion of an underlying lesion.
Assuntos
Gastroscopia , Neoplasias , Biópsia , Clostridium , Feminino , Humanos , Sarcina , EstômagoRESUMO
INTRODUCCIÓN: La calcificación arterial de la infancia es una enfermedad rara, autosómica recesiva, potencialmente letal, caracterizada por la calcificación de la lámina elástica interna de arterias de tamaño grande y mediano con engrosamiento intimal. CASO CLÍNICO: Presentamos el caso de una autopsia clínica de un recién nacido varón pre-término que muestra al nacimiento hidrops fetal y cianosis generalizada. El estudio macroscópico reveló cardiomegalia secundaria a oclusión arterial por calcificación. DISCUSIÓN: Se realiza correlación clínico-histológica de la entidad con hallazgos macro y microscópicos relevantes y actualización de diagnóstico genético
INTRODUCTION: Arterial calcification of infancy is a rare autosomal recessive genetic disorder with extremely poor prognosis characterized by extensive calcification of internal elastic lamina and thickened of intimal tissue of large and medium sized arteries. CASE REPORT: We present the case of a newborn necropsy with hydrops and widespread cyanosis. The internal examination revealed heart enlargement due to occlusive calcification of the arteries. DISCUSSION: The aim of the present report is to provide a correlation of clinical and pathological features. An update of genetic diagnosis is provided
Assuntos
Humanos , Masculino , Recém-Nascido , Calcificação Vascular/complicações , Cardiomegalia/diagnóstico , Cardiomegalia/etiologia , Calcificação Vascular/patologia , AutopsiaRESUMO
INTRODUCTION: Arterial calcification of infancy is a rare autosomal recessive genetic disorder with extremely poor prognosis characterized by extensive calcification of internal elastic lamina and thickened of intimal tissue of large and medium sized arteries. CASE REPORT: We present the case of a newborn necropsy with hydrops and widespread cyanosis. The internal examination revealed heart enlargement due to occlusive calcification of the arteries. DISCUSSION: The aim of the present report is to provide a correlation of clinical and pathological features. An update of genetic diagnosis is provided.
